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Lucy Carter Archives - Psychosis Research Unit
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Lucy Carter

A pilot randomised controlled trial comparing antipsychotic medication, to cognitive behavioural therapy to a combination of both in people with psychosis: rationale, study design and baseline data of the COMPARE trial

Heather Law, Lucy Carter, Rachel Sellers, Richard Emsley, Rory Byrne, Linda Davies, Paul French, Peter M. Haddad, Elizabeth Pitt, Melissa Pyle, David Shiers, Alison R. Yung & Anthony P. Morrison Full Article Abstract Aims: Ongoing NICE guidance recommends research on the clinical and cost effectiveness of psychological treatment alone, compared to antipsychotic medication and compared to psychological treatment and antipsychotic medication combined. The COMPARE study (Cognitive behaviour therapy or Medication for Psychosis- A Randomised Evaluation) was a pilot trial designed to inform a definitive trial to answer this question. Method: COMPARE was a single-site pilot randomised controlled trial to compare a standardised Cognitive Behaviour Therapy (CBT) intervention to treatment with antipsychotic medication (APs) and a combined treatment (CBT plus APs) in adults with psychosis. Participants were assessed using...

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The Impact of Causal Explanations on Outcome in People Experiencing Psychosis: A Systematic Review

Lucy Carter, John Read,Melissa Pyle, Anthony P. Morrison Full Article Abstract Findings suggest that the way an individual understands their experiences has important consequences on subsequent health behaviour. One aspect of an individual's understanding is what they believe has caused their experiences. This has been associated with treatment outcome and attitudes towards mental health problems. The aim of this systematic review was to examine the impact of causal beliefs on treatment outcome and stigma in people experiencing psychosis. Three main databases were searched and 21 articles that investigated various aspects of treatment outcome, and stigma in relation to causal beliefs was included in the review. Overall, there were a small number of replicated findings which limits the interpretation of results. There is an indication that causal explanations...

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