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Publications Archives - Psychosis Research Unit
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An exploration of the relationship between use of safety seeking behaviours and psychosis: A systematic review and meta-analysis

Sarah Tully, Adrian Wells, Anthony P. Morrison Full Article Abstract Safety-seeking behaviours are responses employed to protect against perceived threat. In relation to anxiety disorders, safety-seeking behaviours have been implicated in both the formation and maintenance of distress. Several studies have highlighted similar findings in relation to psychosis; however, this literature has not yet been synthesized. This review is, therefore, being conducted in order to synthesize the literature on safety seeking in people with psychosis to increase the understanding of this relationship. A systematic search identified and included 43 studies comprising 2,592 participants, published between 1995 and 2015. The results indicated that people experiencing psychosis commonly respond to their experiences with behavioural and cognitive strategies intended to manage their difficulties. In relation to safety seeking, avoidance,...


“You’ve got your own demons that you’ve got to fight everyday”: A qualitative exploration of how people respond to the experience of psychosis

Sarah Tully, Adrian Wells, Anthony P. Morrison Full Article   Abstract Objectives Cognitive models of psychosis implicate how people respond to their distressing experiences in the maintenance of such experiences. Safety-seeking behaviours, which are employed in response to a catastrophic misinterpretation of threat, are viewed as unhelpful maintenance factors. However, the concept of safety seeking was developed in relation to anxiety disorders, and there may be additional complexities that apply in relation to the experience of psychosis. The ways in which people respond to their distressing experiences of psychosis are complex, multifaceted, and changeable, and qualitative research is needed to further the understanding of this process. Design A qualitative study was conducted using grounded theory methodology. Method In-depth interviews were conducted with fifteen participants who had experience of psychosis. Results ...


Measuring Common Responses to Psychosis: Assessing the Psychometric Properties of a New Measure

Sarah Tully, Adrian Wells, Melissa Pyle, Jemma Hudson, Andrew Gumley, David Kingdon, Matthias Schwannauer, Douglas Turkington, Anthony P. Morrison Full Article  Abstract Responses to psychotic experiences are central to cognitive models of psychosis. The current study aimed to develop and validate a self-report measure of common responses to the experience of psychosis. This measure is needed as cognitive and behavioural responses are implicated in the maintenance of psychosis, but there is currently no measure that comprehensively assesses these maintaining factors. The Measure of Common Responses to psychosis (MCR) was developed and utilised in a sample of 487 participants who met criteria for treatment-resistant schizophrenia. Principal components analysis using data from 287 participants reduced the initial item pool of 31 items to 15 items with a three...


Young people at risk of psychosis: Their subjective experiences of monitoring and cognitive behaviour therapy in the early detection and intervention evaluation 2 trial

Rory E. Byrne and Anthony P. Morrison Full Article Abstract Objectives To explore participants' experiences of ‘enhanced monitoring’ and cognitive behaviour therapy (CBT) within a randomized controlled trial evaluating early detection and prevention of psychosis (‘early detection and intervention evaluation [EDIE] 2’). Design Semi-structured qualitative interviews were conducted with a sample of participants at the end of their involvement with the trial. Methods Ten young people were interviewed; six males and four females, with a mean age of 27.5. Nine participants identified themselves as White British and one Black British. All participants had received ‘enhanced monitoring’ during the trial, and 8 of 10 also received CBT. Interviews were transcribed verbatim and analysed using thematic analysis to identify central themes within and among participants' accounts. Results Three super-ordinate thematic areas were...


Exploring Service Users’ Perceptions of Cognitive Behavioural Therapy for Psychosis: A User Led Study

Martina Kilbride, Rory Byrne, Jason Price, Lisa Wood, Sarah Barratt, Mary Welford and Anthony P. Morrison Full Article Abstract Background and aims: This study explored individuals’ subjective experiences of Cognitive Behavioural Therapy for psychosis (CBTp) with the aim of identifying coherent themes consistent across individual accounts and any potential barriers to CBTp effectiveness. Method: Semi-structured interviews were conducted with nine individuals with experience of CBTp. A qualitative Interpretive Phenomenological Analysis was used to analyze the data collected to identify common themes. Results: Five super-ordinate themes emerged from our analyses: CBT as a process of person-centred engagement; CBT as an active process of structured learning; CBT helping to improve personal understanding; CBT is hard work; Recovery and outcomes of CBT for psychosis. Conclusions: The theoretical and clinical implications...